Moderate Cosmetic Ingredient

Decapeptide-18

INCI: DECAPEPTIDE-18

CAS Number
Not clearly disclosed in public sources; often sold under trade name CG‑WINT without CAS citation
Function
Hair growth/hair follicle modulation peptide; CG-WINT stimulates formation of new hair follicles and is used in anti-hair-loss and hair thickening products
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted as cosmetic ingredient, but anti-hair-loss or hair growth claims may be viewed as drug claims under FDA; should be limited to cosmetic claims (appearance, volume) to stay in cosmetic category

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Borderline hair growth claims with biological activity on Wnt/follicle pathways; avoid use in leave-on products for children, pregnant women, or on damaged scalp without robust tox data; ensure occupational exposure controls during manufacturing (powder handling)

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Concern Level: Moderate

Frequently Asked Questions

Is Decapeptide-18 safe in cosmetics?

Borderline hair growth claims with biological activity on Wnt/follicle pathways; avoid use in leave-on products for children, pregnant women, or on damaged scalp without robust tox data; ensure occupational exposure controls during manufacturing (powder handling) The EU classifies Decapeptide-18 as "permitted". Safety rating: MODERATE.

Is Decapeptide-18 allowed in the EU?

Decapeptide-18 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decapeptide-18 do in cosmetics?

Decapeptide-18 functions as: Hair growth/hair follicle modulation peptide; CG-WINT stimulates formation of new hair follicles and is used in anti-hair-loss and hair thickening products. It is classified as a cosmetic ingredient in our database. CAS number: Not clearly disclosed in public sources; often sold under trade name CG‑WINT without CAS citation.

What is the Margin of Safety for Decapeptide-18?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Decapeptide-18 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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