Is Decapeptide-22 safe in cosmetics?
Decapeptide-22 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Decapeptide-22
INCI: DECAPEPTIDE-22
Decapeptide-22 (CAS Not uniquely assigned/publicly disclosed; supplier-specific research peptide listings do not provide a CAS.) is a cosmetic cosmetic ingredient functioning as Skin conditioning; anti-ageing/anti-wrinkle, skin repair. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not uniquely assigned/publicly disclosed; supplier-specific research peptide listings do not provide a CAS.
View industrial chemical safety profile →
Function
Skin conditioning; anti-ageing/anti-wrinkle, skin repair
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA prohibition or monograph; regulated under general cosmetic safety requirement for non-drug use. No CIR opinion identified under this exact name.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decapeptide-22.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
peptide
{"trade_name": "Decapeptide 22", "peptide_sequence_amino_acids": "Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr", "peptide_length_residues": "10", "molecular_weight_daltons": "1230", "peptide_class": "enzyme_inhibitor", "mechanism_of_action": "Tyrosinase inhibition and skin brightening", "target_protein_or_receptor": "Tyrosinase/MC1R", "collagen_boost_pct_in_vitro": "0", "elastin_stimulation": "moderate…
Expert Verdict
Expert safety assessment and concern-level summary for Decapeptide-22.
Frequently Asked Questions
Is Decapeptide-22 allowed in the EU?
Decapeptide-22 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decapeptide-22 do in cosmetics?
Decapeptide-22 functions as: Skin conditioning; anti-ageing/anti-wrinkle, skin repair. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned/publicly disclosed; supplier-specific research peptide listings do not provide a CAS..
Compliance Tools
Check Decapeptide-22 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Is Decapeptide-22 in Your Products?
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