Moderate Cosmetic Ingredient

Decapeptide-28

INCI: DECAPEPTIDE-28

CAS Number
Not publicly listed in cosmetic databases; encapsulated biomimetic peptide described in marketing materials.
Function
Hair growth and rejuvenation stimulator; described as activating anagen phase and delaying catagen
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes As a cosmetic, may only claim cosmetic effects (appearance, feel of hair); explicit hair growth or regrowth claims can trigger OTC drug status under US law. No CIR monograph.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mechanism suggests modulation of follicular biology; long-term continuous use in young users or those with scalp disease should be evaluated carefully. Watch for regulatory reclassification risk if claims cross into drug territory.

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Concern Level: Moderate

Frequently Asked Questions

Is Decapeptide-28 safe in cosmetics?

Mechanism suggests modulation of follicular biology; long-term continuous use in young users or those with scalp disease should be evaluated carefully. Watch for regulatory reclassification risk if claims cross into drug territory. The EU classifies Decapeptide-28 as "permitted". Safety rating: MODERATE.

Is Decapeptide-28 allowed in the EU?

Decapeptide-28 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decapeptide-28 do in cosmetics?

Decapeptide-28 functions as: Hair growth and rejuvenation stimulator; described as activating anagen phase and delaying catagen. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in cosmetic databases; encapsulated biomimetic peptide described in marketing materials..

What is the Margin of Safety for Decapeptide-28?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Decapeptide-28 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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