Is Decapeptide-28 safe in cosmetics?
Decapeptide-28 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Decapeptide-28
INCI: DECAPEPTIDE-28
Decapeptide-28 (CAS Not publicly listed in cosmetic databases; encapsulated biomimetic peptide described in marketing materials.) is a cosmetic cosmetic ingredient functioning as Hair growth and rejuvenation stimulator; described as activating anagen phase. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly listed in cosmetic databases; encapsulated biomimetic peptide described in marketing materials.
View industrial chemical safety profile →
Function
Hair growth and rejuvenation stimulator; described as activating anagen phase and delaying catagen
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
As a cosmetic, may only claim cosmetic effects (appearance, feel of hair); explicit hair growth or regrowth claims can trigger OTC drug status under US law. No CIR monograph.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decapeptide-28.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
peptide
{"trade_name": "Decapeptide 28", "peptide_sequence_amino_acids": "Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr", "peptide_length_residues": "10", "molecular_weight_daltons": "1320", "peptide_class": "enzyme_inhibitor", "mechanism_of_action": "Tyrosinase inhibition and skin brightening", "target_protein_or_receptor": "Tyrosinase/MC1R", "collagen_boost_pct_in_vitro": "0", "elastin_stimulation": "moderate…
Expert Verdict
Expert safety assessment and concern-level summary for Decapeptide-28.
Frequently Asked Questions
Is Decapeptide-28 allowed in the EU?
Decapeptide-28 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decapeptide-28 do in cosmetics?
Decapeptide-28 functions as: Hair growth and rejuvenation stimulator; described as activating anagen phase and delaying catagen. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in cosmetic databases; encapsulated biomimetic peptide described in marketing materials..
Compliance Tools
Check Decapeptide-28 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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