NOAEL Studies
Cosmetic Ingredient
Decene NOAEL Studies
INCI: DECENE
CAS: 872-05-9
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ECHA 12 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ECHA | LOEL | 100 | mg/kg bw/day | rat | oral: gavage | - | screening for reproductive / developmental toxicity | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=8d89f8e1-4a8d-4388-9355-cab992662c43_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=8d89f8e1-4a8d-4388-9355-cab992662c43/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2014; ReportDate=2014-09-25; basis=other:; key_result=false; entry_uuid=5a0c311f-250c-4386-adc3-2007618774c8 |
| ECHA | NOAEL | 1000 | mg/kg bw/day | rat | oral: gavage | - | screening for reproductive / developmental toxicity | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=b6f4e4b0-5e58-4b79-b9f4-0f617d3caaf6_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=b6f4e4b0-5e58-4b79-b9f4-0f617d3caaf6/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2014; ReportDate=2014-09-25; basis=other:; key_result=true; entry_uuid=b7900f88-cff0-4c94-b02b-baa5d3fd6002 |
| ECHA | NOAEL | 500 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=20160d95-7dbc-4fbf-8524-0323f8b0cde2_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=20160d95-7dbc-4fbf-8524-0323f8b0cde2/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2015; ReportDate=2015-09-13; basis=other:; key_result=true; entry_uuid=172d9b1f-8477-43fc-a728-3cb4ba25c318 |
| ECHA | NOAEL | 101 | mg/kg bw/day | rat | oral: gavage | - | neurotoxicity: short-term oral | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=ae35efc7-b0a3-4907-9caa-d86ca46e709e_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=ae35efc7-b0a3-4907-9caa-d86ca46e709e/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=Neurotoxicity; literature=Name=Unnamed; ReferenceYear=1994; ReportDate=1994-03-11; basis=other:; key_result=false; entry_uuid=8ce131d9-6366-4f78-a65b-7ad7016a829c |
| ECHA | NOAEL | 1010 | mg/kg bw/day | rat | oral: gavage | - | neurotoxicity: short-term oral | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=ae35efc7-b0a3-4907-9caa-d86ca46e709e_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=ae35efc7-b0a3-4907-9caa-d86ca46e709e/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=Neurotoxicity; literature=Name=Unnamed; ReferenceYear=1994; ReportDate=1994-03-11; basis=other:; key_result=false; entry_uuid=213f55e7-cadb-4a5c-98a0-1f0d64156651 |
| ECHA | NOAEL | 350 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=150fd44f-8316-44a3-a30b-791f246a8043_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=150fd44f-8316-44a3-a30b-791f246a8043/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1994; ReportDate=1994-10-19; basis=other:; key_result=true; entry_uuid=d6938f35-f72d-4673-95f4-47875affdb46 |
| ECHA | NOEL | 300 | mg/kg bw/day | rat | oral: gavage | - | screening for reproductive / developmental toxicity | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=b6f4e4b0-5e58-4b79-b9f4-0f617d3caaf6_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=b6f4e4b0-5e58-4b79-b9f4-0f617d3caaf6/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2014; ReportDate=2014-09-25; basis=other:; key_result=false; entry_uuid=dc042bd7-f722-4c32-abb0-53dc717d1e1c |
| ECHA | NOEL | 1000 | mg/kg bw/day | rat | oral: gavage | - | developmental toxicity | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=30f9415d-0018-471b-9efc-491d75437f48_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=30f9415d-0018-471b-9efc-491d75437f48/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2015; ReportDate=2015-12-17; basis=other:; key_result=true; entry_uuid=80fb1015-6ef9-4f3c-8156-f56f0571add8 |
| ECHA | NOEL | 100 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=f6f06f38-a8c6-437f-91f7-e202d39afe0f_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=f6f06f38-a8c6-437f-91f7-e202d39afe0f/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2015; ReportDate=2015-11-26; basis=other:; key_result=true; entry_uuid=b1115c5e-aa51-4075-b0aa-542d3a8f2460 |
| ECHA | NOEL | 20 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=82ae59be-b166-4109-bdc7-2e660e104961.i6z; document=20160d95-7dbc-4fbf-8524-0323f8b0cde2_82ae59be-b166-4109-bdc7-2e660e104961.i6d; document_key=20160d95-7dbc-4fbf-8524-0323f8b0cde2/82ae59be-b166-4109-bdc7-2e660e104961; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2015; ReportDate=2015-09-13; basis=other:; key_result=true; entry_uuid=408e530c-704a-415b-b80d-4647d2ffa759 |
| ECHA | NOAEC | =3000 | ppm | Rat | inhalation | subchronic; 13 weeks | subchronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/1649/7/6/3?documentUUID=82ae59be-b166-4109-bdc7-2e660e104961; YEAR=2004; ORIGINAL_YEAR=2004; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15827212_15828593:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_91738c00f8960f238b19b02ace2da51e |
| ECHA | NOAEC | =17211.1 | mg/m3 | Rat | inhalation | subchronic; 13 weeks | subchronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15149/7/6/3?documentUUID=5a5052b8-444b-433d-b1a8-f3532a2779f7; YEAR=1963; ORIGINAL_YEAR=1963; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829009_15829104:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4706a21968c109c3698a84c936ed5ed9 |
openFDA substances 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 7O4U4C718P | UNII | - | - | - | chemical | - |