Defatted Hydrangea Macrophylla Flower

INCI: DEFATTED HYDRANGEA MACROPHYLLA FLOWER

CAS Number
Not uniquely assigned; parent Hydrangea macrophylla extract CAS 97676-21-0
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted - not prohibited or restricted under 21 CFR. No CIR review.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Defatted Hydrangea macrophylla flower is a skin conditioning agent with limited cosmetic safety data; contains hydrangenol (a dihydroisocoumarin) with hepatotoxic effects in animal models and potentially cyanogenic glycosides, but no regulatory restrictions exist.

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Concern Level: Moderate

Frequently Asked Questions

Is Defatted Hydrangea Macrophylla Flower safe in cosmetics?

Defatted Hydrangea macrophylla flower is a skin conditioning agent with limited cosmetic safety data; contains hydrangenol (a dihydroisocoumarin) with hepatotoxic effects in animal models and potentially cyanogenic glycosides, but no regulatory restrictions exist. The EU classifies Defatted Hydrangea Macrophylla Flower as "permitted". Safety rating: MODERATE.

Is Defatted Hydrangea Macrophylla Flower allowed in the EU?

Defatted Hydrangea Macrophylla Flower EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Defatted Hydrangea Macrophylla Flower do in cosmetics?

Defatted Hydrangea Macrophylla Flower functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned; parent Hydrangea macrophylla extract CAS 97676-21-0.

What is the Margin of Safety for Defatted Hydrangea Macrophylla Flower?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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