Dehydrolatanoprost

INCI: DEHYDROLATANOPROST

CAS Number
Not confirmed in CosIng (structurally related to Latanoprost, CAS 130209-82-4)
Function
Eyelash conditioning and growth promotion; prostaglandin analogue class
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted under current FDA rules; however, FDA may classify eyelash growth products as drugs if therapeutic claims are made

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High-risk ingredient: prostaglandin analogue with documented adverse effects including iris pigmentation changes, periorbital fat atrophy, eyelid skin darkening, and potential intraocular pressure changes; Sweden has restricted eyelash serums containing prostaglandin analogues; borderline cosmetic/medicinal classification; SCCS has identified this ingredient class as a priority concern.

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Concern Level: High

Frequently Asked Questions

Is Dehydrolatanoprost safe in cosmetics?

High-risk ingredient: prostaglandin analogue with documented adverse effects including iris pigmentation changes, periorbital fat atrophy, eyelid skin darkening, and potential intraocular pressure changes; Sweden has restricted eyelash serums containing prostaglandin analogues; borderline cosmetic/medicinal classification; SCCS has identified this ingredient class as a priority concern. The EU classifies Dehydrolatanoprost as "permitted". Safety rating: POOR.

Is Dehydrolatanoprost allowed in the EU?

Dehydrolatanoprost EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dehydrolatanoprost do in cosmetics?

Dehydrolatanoprost functions as: Eyelash conditioning and growth promotion; prostaglandin analogue class. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in CosIng (structurally related to Latanoprost, CAS 130209-82-4).

What is the Margin of Safety for Dehydrolatanoprost?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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