Is Diglycosyl Hexapeptide-2 safe in cosmetics?
Diglycosyl Hexapeptide-2 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
MODERATE
Cosmetic Ingredient
Diglycosyl Hexapeptide-2
INCI: DIGLYCOSYL HEXAPEPTIDE-2
Diglycosyl Hexapeptide-2 (CAS Not publicly listed (proprietary peptide derivative)) is a cosmetic cosmetic ingredient functioning as Skin-lightening / anti-pigmentation agent — glycosylated derivative of. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
CAS Number
Not publicly listed (proprietary peptide derivative)
View industrial chemical safety profile →
Function
Skin-lightening / anti-pigmentation agent — glycosylated derivative of Hexapeptide-2 (α-MSH antagonist, reduces melanin synthesis)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no CFR prohibition; however, skin-lightening claims may trigger FDA OTC drug scrutiny
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diglycosyl Hexapeptide-2.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Diglycosyl Hexapeptide-2 — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Diglycosyl Hexapeptide-2 allowed in the EU?
Diglycosyl Hexapeptide-2 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Diglycosyl Hexapeptide-2 do in cosmetics?
Diglycosyl Hexapeptide-2 functions as: Skin-lightening / anti-pigmentation agent — glycosylated derivative of Hexapeptide-2 (α-MSH antagonist, reduces melanin synthesis). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed (proprietary peptide derivative).
Compliance Tools
Check Diglycosyl Hexapeptide-2 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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