Is Diglycosyl Hexapeptide-2 safe in cosmetics?
Diglycosyl Hexapeptide-2 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Diglycosyl Hexapeptide-2
INCI: DIGLYCOSYL HEXAPEPTIDE-2
Diglycosyl Hexapeptide-2 (CAS Not publicly listed (proprietary peptide derivative)) is a cosmetic cosmetic ingredient functioning as Skin-lightening / anti-pigmentation agent — glycosylated derivative of. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly listed (proprietary peptide derivative)
View industrial chemical safety profile →
Function
Skin-lightening / anti-pigmentation agent — glycosylated derivative of Hexapeptide-2 (α-MSH antagonist, reduces melanin synthesis)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no CFR prohibition; however, skin-lightening claims may trigger FDA OTC drug scrutiny
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diglycosyl Hexapeptide-2.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Diglycosyl Hexapeptide-2.
Frequently Asked Questions
Is Diglycosyl Hexapeptide-2 allowed in the EU?
Diglycosyl Hexapeptide-2 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Diglycosyl Hexapeptide-2 do in cosmetics?
Diglycosyl Hexapeptide-2 functions as: Skin-lightening / anti-pigmentation agent — glycosylated derivative of Hexapeptide-2 (α-MSH antagonist, reduces melanin synthesis). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed (proprietary peptide derivative).
Compliance Tools
Check Diglycosyl Hexapeptide-2 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Diglycosyl Hexapeptide-2 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Diglycosyl Hexapeptide-2 in your formulation.