Dihydroxymethoxychalcone

INCI: DIHYDROXYMETHOXYCHALCONE

CAS Number
Not confirmed for specific INCI entry
Function
Antioxidant, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; no CIR review identified

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Related 2โ€ฒ,4โ€ฒ-dihydroxychalcone carries GHS H315/H319/H335 warnings for skin/eye/respiratory irritation; positional isomer differentiation is critical to confirm exact structure versus GHS-classified analogs.

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Concern Level: Moderate

Frequently Asked Questions

Is Dihydroxymethoxychalcone safe in cosmetics?

Related 2โ€ฒ,4โ€ฒ-dihydroxychalcone carries GHS H315/H319/H335 warnings for skin/eye/respiratory irritation; positional isomer differentiation is critical to confirm exact structure versus GHS-classified analogs. The EU classifies Dihydroxymethoxychalcone as "permitted". Safety rating: MODERATE.

Is Dihydroxymethoxychalcone allowed in the EU?

Dihydroxymethoxychalcone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dihydroxymethoxychalcone do in cosmetics?

Dihydroxymethoxychalcone functions as: Antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed for specific INCI entry.

What is the Margin of Safety for Dihydroxymethoxychalcone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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