Diisopropyl Nonyl Phosphine Oxide

INCI: DIISOPROPYL NONYL PHOSPHINE OXIDE

CAS Number
Not widely registered — structural analog of CAS 1487170-15-9 (heptyl variant) with C9 alkyl chain
Function
Solubilizer / emollient / penetration enhancer
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Longer C9 alkyl chain increases lipophilicity with primary risk from penetration enhancement of co-ingredients; no CIR/SCCS review or published NOAEL established.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Diisopropyl Nonyl Phosphine Oxide safe in cosmetics?

Longer C9 alkyl chain increases lipophilicity with primary risk from penetration enhancement of co-ingredients; no CIR/SCCS review or published NOAEL established. The EU classifies Diisopropyl Nonyl Phosphine Oxide as "permitted". Safety rating: MODERATE.

Is Diisopropyl Nonyl Phosphine Oxide allowed in the EU?

Diisopropyl Nonyl Phosphine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diisopropyl Nonyl Phosphine Oxide do in cosmetics?

Diisopropyl Nonyl Phosphine Oxide functions as: Solubilizer / emollient / penetration enhancer. It is classified as a cosmetic ingredient in our database. CAS number: Not widely registered — structural analog of CAS 1487170-15-9 (heptyl variant) with C9 alkyl chain.

What is the Margin of Safety for Diisopropyl Nonyl Phosphine Oxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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