Dimethicone Hydroxypropyl Trimonium Chloride

INCI: DIMETHICONE HYDROXYPROPYL TRIMONIUM CHLORIDE

CAS Number
Not individually assigned (quaternary ammonium-functional silicone)
Function
Hair conditioning, antistatic agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not specifically restricted under 21 CFR; CIR has reviewed methicone family

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Quaternary ammonium compounds can be irritating at high concentrations on compromised skin; verify use concentration aligns with CIR-reviewed range; if in leave-on product at >2%, request specific irritation data.

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Concern Level: Low

Frequently Asked Questions

Is Dimethicone Hydroxypropyl Trimonium Chloride safe in cosmetics?

Quaternary ammonium compounds can be irritating at high concentrations on compromised skin; verify use concentration aligns with CIR-reviewed range; if in leave-on product at >2%, request specific irritation data. The EU classifies Dimethicone Hydroxypropyl Trimonium Chloride as "permitted". Safety rating: GOOD.

Is Dimethicone Hydroxypropyl Trimonium Chloride allowed in the EU?

Dimethicone Hydroxypropyl Trimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethicone Hydroxypropyl Trimonium Chloride do in cosmetics?

Dimethicone Hydroxypropyl Trimonium Chloride functions as: Hair conditioning, antistatic agent. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (quaternary ammonium-functional silicone).

What is the Margin of Safety for Dimethicone Hydroxypropyl Trimonium Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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