Dimethicone/Aminopropyl Silsesquioxane Copolymer

INCI: DIMETHICONE/AMINOPROPYL SILSESQUIOXANE COPOLYMER

CAS Number
Not uniquely assigned (copolymer)
Function
Hair conditioning, film forming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; CIR reviewed aminopropyl dimethicone as safe when non-irritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Aminopropyl moiety can elevate pH; formulation pH must be controlled. Silsesquioxane cage structure is chemically inert. Monitor D4/D5 residuals.

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Concern Level: Moderate

Frequently Asked Questions

Is Dimethicone/Aminopropyl Silsesquioxane Copolymer safe in cosmetics?

Aminopropyl moiety can elevate pH; formulation pH must be controlled. Silsesquioxane cage structure is chemically inert. Monitor D4/D5 residuals. The EU classifies Dimethicone/Aminopropyl Silsesquioxane Copolymer as "permitted". Safety rating: GOOD.

Is Dimethicone/Aminopropyl Silsesquioxane Copolymer allowed in the EU?

Dimethicone/Aminopropyl Silsesquioxane Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethicone/Aminopropyl Silsesquioxane Copolymer do in cosmetics?

Dimethicone/Aminopropyl Silsesquioxane Copolymer functions as: Hair conditioning, film forming. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (copolymer).

What is the Margin of Safety for Dimethicone/Aminopropyl Silsesquioxane Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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