Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Dimethylacrylamide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 10 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOEL | 40 mg/kg bw/day | oral | mouse | oral | REACH |
Expert Verdict
Acute oral and dermal toxicity (H301+H311); must only be present as trace residual in finished polymers with acrylamide impurity limit of ≤5 ppm; this monomer should never appear as a named ingredient in finished products
Frequently Asked Questions
Is Dimethylacrylamide safe in cosmetics?
Acute oral and dermal toxicity (H301+H311); must only be present as trace residual in finished polymers with acrylamide impurity limit of ≤5 ppm; this monomer should never appear as a named ingredient in finished products The EU classifies Dimethylacrylamide as "permitted". Safety rating: POOR. 3 toxicological study endpoint(s) are available in our database.
Is Dimethylacrylamide allowed in the EU?
Dimethylacrylamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethylacrylamide do in cosmetics?
Dimethylacrylamide functions as: Monomer precursor for copolymers; not intended for direct cosmetic use. It is classified as a cosmetic ingredient in our database. CAS number: 2680-03-7.
What is the Margin of Safety for Dimethylacrylamide?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dimethylacrylamide?
The NOAEL (No Observed Adverse Effect Level) for Dimethylacrylamide is 5 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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