Good Cosmetic Ingredient NOAEL Data

Dimethylheptenal

INCI: DIMETHYLHEPTENAL

CAS Number
106-72-9
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; RIFM-assessed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Dimethylheptenal. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 160 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOEL 300 mg/kg bw/day oral rat oral REACH

Expert Verdict

Aldehyde class fragrance with potential for mild skin and mucous membrane irritation at high concentrations; IFRA use restrictions and RIFM environmental assessment apply.

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Concern Level: Moderate

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Dimethylheptenal safe in cosmetics?

Aldehyde class fragrance with potential for mild skin and mucous membrane irritation at high concentrations; IFRA use restrictions and RIFM environmental assessment apply. The EU classifies Dimethylheptenal as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Dimethylheptenal allowed in the EU?

Dimethylheptenal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethylheptenal do in cosmetics?

Dimethylheptenal functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 106-72-9.

What is the Margin of Safety for Dimethylheptenal?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Dimethylheptenal?

The NOAEL (No Observed Adverse Effect Level) for Dimethylheptenal is 160 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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