Regulatory Status
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Safety Data
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Expert Verdict
Dimethylmethoxy Chromanol (Lipochroman) is a patented bioinspired antioxidant with demonstrated ROS, RNS, and RCS scavenging activity and negligible cytotoxicity in vitro. Freely permitted in the EU and US with no annex restrictions. However, the absence of published dermal absorption data, NOAEL, MoS, and sensitization studies means safety substantiation relies entirely on proprietary Lubrizol/Lipotec dossiers.
Regulatory Flags
Frequently Asked Questions
Is Dimethylmethoxy Chromanol safe in cosmetics?
Dimethylmethoxy Chromanol (Lipochroman) is a patented bioinspired antioxidant with demonstrated ROS, RNS, and RCS scavenging activity and negligible cytotoxicity in vitro. Freely permitted in the EU and US with no annex restrictions. However, the absence of published dermal absorption data, NOAEL, MoS, and sensitization studies means safety substantiation relies entirely on proprietary Lubrizol/Lipotec dossiers. The EU classifies Dimethylmethoxy Chromanol as "permitted". Safety rating: GOOD.
Is Dimethylmethoxy Chromanol allowed in the EU?
Dimethylmethoxy Chromanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethylmethoxy Chromanol do in cosmetics?
Dimethylmethoxy Chromanol functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 83923-51-7.
What is the Margin of Safety for Dimethylmethoxy Chromanol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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