Dinonoxynol-9 Citrate

INCI: DINONOXYNOL-9 CITRATE

CAS Number
Not individually assigned (no verified CAS located)
Function
Surfactant / emulsifier (citrate ester of dinonylphenol ethoxylate)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR found nonoxynols (including -9 derivatives) safe; higher-MW nonoxynols (โ‰ฅ9 EO) have lower irritation potential than lower-MW variants

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Nonoxynol-9 exhibits documented vaginal mucosal irritation potential and endocrine disruption concerns from residual dinonylphenol; citrate ester form shares nonylphenol ethoxylate class concerns.

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Concern Level: Moderate

Frequently Asked Questions

Is Dinonoxynol-9 Citrate safe in cosmetics?

Nonoxynol-9 exhibits documented vaginal mucosal irritation potential and endocrine disruption concerns from residual dinonylphenol; citrate ester form shares nonylphenol ethoxylate class concerns. The EU classifies Dinonoxynol-9 Citrate as "prohibited". Safety rating: MODERATE.

Is Dinonoxynol-9 Citrate allowed in the EU?

Dinonoxynol-9 Citrate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Dinonoxynol-9 Citrate do in cosmetics?

Dinonoxynol-9 Citrate functions as: Surfactant / emulsifier (citrate ester of dinonylphenol ethoxylate). It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (no verified CAS located).

What is the Margin of Safety for Dinonoxynol-9 Citrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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