Dioscorea Villosa Root Extract

INCI: DIOSCOREA VILLOSA ROOT EXTRACT

CAS Number
90147-49-2
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not on FDA prohibited/restricted list (21 CFR 700); CIR Expert Panel concluded safe as used (2004, reaffirmed 2023)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Diosgenin content must be characterized with upper limit approximately 3.5% via specified extraction; estrogenic activity of diosgenin at high concentrations noted; safety conclusion valid only for extracts with chemical profiles matching CIR-assessed material.

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Dioscorea Villosa Root Extract safe in cosmetics?

Diosgenin content must be characterized with upper limit approximately 3.5% via specified extraction; estrogenic activity of diosgenin at high concentrations noted; safety conclusion valid only for extracts with chemical profiles matching CIR-assessed material. The EU classifies Dioscorea Villosa Root Extract as "permitted". Safety rating: GOOD.

Is Dioscorea Villosa Root Extract allowed in the EU?

Dioscorea Villosa Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dioscorea Villosa Root Extract do in cosmetics?

Dioscorea Villosa Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90147-49-2.

What is the Margin of Safety for Dioscorea Villosa Root Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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