Diospyros Lotus Leaf Extract

INCI: DIOSPYROS LOTUS LEAF EXTRACT

CAS Number
Not specifically assigned in CosIng (genus-level ingredient)
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Pharmacological activity demonstrated via STAT3/IP3R1 inhibition in preclinical models; insufficient data to determine whether topical doses reach pharmacologically active levels or pose safety risks without formal dermal toxicology studies.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Diospyros Lotus Leaf Extract safe in cosmetics?

Pharmacological activity demonstrated via STAT3/IP3R1 inhibition in preclinical models; insufficient data to determine whether topical doses reach pharmacologically active levels or pose safety risks without formal dermal toxicology studies. The EU classifies Diospyros Lotus Leaf Extract as "permitted". Safety rating: MODERATE.

Is Diospyros Lotus Leaf Extract allowed in the EU?

Diospyros Lotus Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diospyros Lotus Leaf Extract do in cosmetics?

Diospyros Lotus Leaf Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned in CosIng (genus-level ingredient).

What is the Margin of Safety for Diospyros Lotus Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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