Diospyros Mespiliformis Leaf Extract
INCI: DIOSPYROS MESPILIFORMIS LEAF EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
In-vivo studies show it is not toxic at tested doses, but formal dermal NOAEL is absent; demonstrated pharmacological activity (IL-1, IL-8, MMP-1 suppression) means active concentrations must be defined; traditional medicinal use in Africa supports general safety but not cosmetic-specific dermal safety.
Regulatory Flags
Frequently Asked Questions
Is Diospyros Mespiliformis Leaf Extract safe in cosmetics?
In-vivo studies show it is not toxic at tested doses, but formal dermal NOAEL is absent; demonstrated pharmacological activity (IL-1, IL-8, MMP-1 suppression) means active concentrations must be defined; traditional medicinal use in Africa supports general safety but not cosmetic-specific dermal safety. The EU classifies Diospyros Mespiliformis Leaf Extract as "permitted". Safety rating: MODERATE.
Is Diospyros Mespiliformis Leaf Extract allowed in the EU?
Diospyros Mespiliformis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diospyros Mespiliformis Leaf Extract do in cosmetics?
Diospyros Mespiliformis Leaf Extract functions as: Skin conditioning, anti-pollution, anti-aging. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned.
What is the Margin of Safety for Diospyros Mespiliformis Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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