Dipropylene Glycol Salicylate

INCI: DIPROPYLENE GLYCOL SALICYLATE

CAS Number
Not confirmed from search results
Function
Surfactant, viscosity regulator, skin and hair conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Salicylic acid is an OTC drug active (21 CFR 310/333). Ester form for cosmetic use requires careful positioning to avoid drug classification.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Salicylic acid release upon hydrolysis triggers Annex III restrictions. Must quantify free salicylic acid and potential release. Aspirin cross-reactivity risk. CAS number data gap. Not recommended without full hydrolysis study and compliance check.

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Concern Level: Moderate

Frequently Asked Questions

Is Dipropylene Glycol Salicylate safe in cosmetics?

Salicylic acid release upon hydrolysis triggers Annex III restrictions. Must quantify free salicylic acid and potential release. Aspirin cross-reactivity risk. CAS number data gap. Not recommended without full hydrolysis study and compliance check. The EU classifies Dipropylene Glycol Salicylate as "restricted". Safety rating: MODERATE.

Is Dipropylene Glycol Salicylate allowed in the EU?

Dipropylene Glycol Salicylate EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Dipropylene Glycol Salicylate do in cosmetics?

Dipropylene Glycol Salicylate functions as: Surfactant, viscosity regulator, skin and hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from search results.

What is the Margin of Safety for Dipropylene Glycol Salicylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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