Disodium Bis-Dioleoyl Glycerophosphoglycerin

INCI: DISODIUM BIS-DIOLEOYL GLYCEROPHOSPHOGLYCERIN

CAS Number
Not publicly assigned (CosIng/COSMILE entry exists without CAS)
Function
Skin conditioning agent (phospholipid derivative, emollient/membrane mimetic)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed in 21 CFR ยง700; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Synthetic phospholipid with data gaps for genotoxicity and repeated-dose dermal toxicity; supplier-level testing shows no sensitization at tested concentrations.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Disodium Bis-Dioleoyl Glycerophosphoglycerin safe in cosmetics?

Synthetic phospholipid with data gaps for genotoxicity and repeated-dose dermal toxicity; supplier-level testing shows no sensitization at tested concentrations. The EU classifies Disodium Bis-Dioleoyl Glycerophosphoglycerin as "permitted". Safety rating: MODERATE.

Is Disodium Bis-Dioleoyl Glycerophosphoglycerin allowed in the EU?

Disodium Bis-Dioleoyl Glycerophosphoglycerin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Bis-Dioleoyl Glycerophosphoglycerin do in cosmetics?

Disodium Bis-Dioleoyl Glycerophosphoglycerin functions as: Skin conditioning agent (phospholipid derivative, emollient/membrane mimetic). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (CosIng/COSMILE entry exists without CAS).

What is the Margin of Safety for Disodium Bis-Dioleoyl Glycerophosphoglycerin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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