Good Cosmetic Ingredient NOAEL Data

Disodium Cetearyl Sulfosuccinate

INCI: DISODIUM CETEARYL SULFOSUCCINATE

CAS Number
91697-07-3
Function
Surfactant - cleansing, foaming (anionic monoester sulfosuccinate)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted - no 21 CFR restriction; included as proposed add-on in CIR 2013 alkyl sulfosuccinate re-review, supported by read-across from diethylhexyl sodium sulfosuccinate

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Disodium Cetearyl Sulfosuccinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 60 mg/kg bw/day oral rat oral REACH
NOAEL 60 mg/kg bw/day oral rat oral REACH

Expert Verdict

CIR stressed care to avoid irritancy, especially in prolonged-contact products; original safe concentration limit for lead compound was 0.42%, later amended to safe as used (max ~4.4%); cetearyl alcohol component previously reviewed and found safe

โš ๏ธ
Concern Level: Low

Frequently Asked Questions

Is Disodium Cetearyl Sulfosuccinate safe in cosmetics?

CIR stressed care to avoid irritancy, especially in prolonged-contact products; original safe concentration limit for lead compound was 0.42%, later amended to safe as used (max ~4.4%); cetearyl alcohol component previously reviewed and found safe The EU classifies Disodium Cetearyl Sulfosuccinate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Disodium Cetearyl Sulfosuccinate allowed in the EU?

Disodium Cetearyl Sulfosuccinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Cetearyl Sulfosuccinate do in cosmetics?

Disodium Cetearyl Sulfosuccinate functions as: Surfactant - cleansing, foaming (anionic monoester sulfosuccinate). It is classified as a cosmetic ingredient in our database. CAS number: 91697-07-3.

What is the Margin of Safety for Disodium Cetearyl Sulfosuccinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Disodium Cetearyl Sulfosuccinate?

The NOAEL (No Observed Adverse Effect Level) for Disodium Cetearyl Sulfosuccinate is 60 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

๐Ÿ“ฑ

Is Disodium Cetearyl Sulfosuccinate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Disodium Cetearyl Sulfosuccinate in your formulation.