Disodium Etidronate

INCI: DISODIUM ETIDRONATE

CAS Number
7414-83-7
Function
Chelating agent that sequesters metal ions to stabilize formulations
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 1.5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with no specific CFR restriction. CIR reviewed etidronic acid and salts.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU restricted ingredient with 1.5% concentration limit. Exceeding permitted concentrations can cause irritation and must be labeled on product. Systemic bisphosphonate effects at high oral doses are not relevant at cosmetic use levels.

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Concern Level: Moderate

Frequently Asked Questions

Is Disodium Etidronate safe in cosmetics?

EU restricted ingredient with 1.5% concentration limit. Exceeding permitted concentrations can cause irritation and must be labeled on product. Systemic bisphosphonate effects at high oral doses are not relevant at cosmetic use levels. The EU classifies Disodium Etidronate as "restricted". Safety rating: GOOD.

Is Disodium Etidronate allowed in the EU?

Disodium Etidronate EU regulatory status: restricted. Maximum allowed concentration: 1.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Etidronate do in cosmetics?

Disodium Etidronate functions as: Chelating agent that sequesters metal ions to stabilize formulations. It is classified as a cosmetic ingredient in our database. CAS number: 7414-83-7.

What is the Margin of Safety for Disodium Etidronate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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