Disodium Isostearoamphodiacetate

INCI: DISODIUM ISOSTEAROAMPHODIACETATE

CAS Number
Not publicly assigned (structural analog: Disodium Cocoamphodiacetate, 68650-39-5)
Function
Amphoteric surfactant — cleansing, foam boosting, hair/skin conditioning
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no restriction under 21 CFR 700; CIR safe as used (amphoacetates class, 2023)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential aminoethylethanolamine (AEEA) impurity (4.9–130 ppm reported in amphoteric trade materials); some irritation noted under occlusive patch conditions.

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Concern Level: Low

Frequently Asked Questions

Is Disodium Isostearoamphodiacetate safe in cosmetics?

Potential aminoethylethanolamine (AEEA) impurity (4.9–130 ppm reported in amphoteric trade materials); some irritation noted under occlusive patch conditions. The EU classifies Disodium Isostearoamphodiacetate as "permitted". Safety rating: GOOD.

Is Disodium Isostearoamphodiacetate allowed in the EU?

Disodium Isostearoamphodiacetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Isostearoamphodiacetate do in cosmetics?

Disodium Isostearoamphodiacetate functions as: Amphoteric surfactant — cleansing, foam boosting, hair/skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (structural analog: Disodium Cocoamphodiacetate, 68650-39-5).

What is the Margin of Safety for Disodium Isostearoamphodiacetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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