Disodium PEG-12 Dimethicone Sulfosuccinate

INCI: DISODIUM PEG-12 DIMETHICONE SULFOSUCCINATE

CAS Number
157090-37-4
Function
Surfactant – cleansing, hydrotrope; extra-mild silicone-derived surfactant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no FDA prohibition; NICNAS Full Public Report assessed as low concern

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Eye irritation potential in concentrate with transient corneal opacity, erythema, and oedema; monitor final product concentration due to sensitization concerns. Ethoxylated ingredient—verify 1,4-dioxane and EO residuals.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen peg-ingredient

Frequently Asked Questions

Is Disodium PEG-12 Dimethicone Sulfosuccinate safe in cosmetics?

Eye irritation potential in concentrate with transient corneal opacity, erythema, and oedema; monitor final product concentration due to sensitization concerns. Ethoxylated ingredient—verify 1,4-dioxane and EO residuals. The EU classifies Disodium PEG-12 Dimethicone Sulfosuccinate as "permitted". Safety rating: GOOD.

Is Disodium PEG-12 Dimethicone Sulfosuccinate allowed in the EU?

Disodium PEG-12 Dimethicone Sulfosuccinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium PEG-12 Dimethicone Sulfosuccinate do in cosmetics?

Disodium PEG-12 Dimethicone Sulfosuccinate functions as: Surfactant – cleansing, hydrotrope; extra-mild silicone-derived surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 157090-37-4.

What is the Margin of Safety for Disodium PEG-12 Dimethicone Sulfosuccinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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