Disodium Salicylphosphate

INCI: DISODIUM SALICYLPHOSPHATE

CAS Number
Not confirmed in major CAS databases; molecular formula C₇H₅O₆P·2Na per Korean KCIA registry
Function
Antioxidant, skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Not prohibited or restricted. CIR reviewed salicylates broadly — salicylic acid safe at established concentrations.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Phosphate ester may hydrolyze in formulation or on skin to release free salicylic acid, which triggers EU restrictions (≤2% in other products, ≤0.5% as preservative). Not for use in products for children under 3 years. Potential endocrine activity flagged by SCCS for free salicylic acid.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Disodium Salicylphosphate safe in cosmetics?

Phosphate ester may hydrolyze in formulation or on skin to release free salicylic acid, which triggers EU restrictions (≤2% in other products, ≤0.5% as preservative). Not for use in products for children under 3 years. Potential endocrine activity flagged by SCCS for free salicylic acid. The EU classifies Disodium Salicylphosphate as "restricted". Safety rating: MODERATE.

Is Disodium Salicylphosphate allowed in the EU?

Disodium Salicylphosphate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Salicylphosphate do in cosmetics?

Disodium Salicylphosphate functions as: Antioxidant, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in major CAS databases; molecular formula C₇H₅O₆P·2Na per Korean KCIA registry.

What is the Margin of Safety for Disodium Salicylphosphate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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