Disodium Uridine Phosphate

INCI: DISODIUM URIDINE PHOSPHATE

CAS Number
3387-36-8 (Uridine 5'-monophosphate disodium salt)
Function
Skin Conditioning — nucleotide derivative claimed to support DNA repair mechanisms
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gap — no dedicated CIR or SCCS assessment for cosmetic use; naturally occurring metabolite with favorable theoretical profile, but standalone safety dossier is thin

⚠️
Concern Level: Low

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Disodium Uridine Phosphate safe in cosmetics?

Data gap — no dedicated CIR or SCCS assessment for cosmetic use; naturally occurring metabolite with favorable theoretical profile, but standalone safety dossier is thin The EU classifies Disodium Uridine Phosphate as "permitted". Safety rating: GOOD.

Is Disodium Uridine Phosphate allowed in the EU?

Disodium Uridine Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Disodium Uridine Phosphate do in cosmetics?

Disodium Uridine Phosphate functions as: Skin Conditioning — nucleotide derivative claimed to support DNA repair mechanisms. It is classified as a cosmetic ingredient in our database. CAS number: 3387-36-8 (Uridine 5'-monophosphate disodium salt).

What is the Margin of Safety for Disodium Uridine Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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