Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Disoydimonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 40 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
QAC class surfactant with documented local irritant effects at high concentrations and potential soy allergen traceability concerns requiring ingredient labeling.
Regulatory Flags
Frequently Asked Questions
Is Disoydimonium Chloride safe in cosmetics?
QAC class surfactant with documented local irritant effects at high concentrations and potential soy allergen traceability concerns requiring ingredient labeling. The EU classifies Disoydimonium Chloride as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is Disoydimonium Chloride allowed in the EU?
Disoydimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Disoydimonium Chloride do in cosmetics?
Disoydimonium Chloride functions as: Antistatic, hair conditioning, emulsifying, surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 68783-78-8.
What is the Margin of Safety for Disoydimonium Chloride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Disoydimonium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Disoydimonium Chloride is 40 mg/kg bw/day based on a dermal study via dermal route in code:3484. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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