CAS Number
9007-49-2
Function
Skin conditioning agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no 21 CFR restriction; general cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Source-origin documentation essential: bovine-derived DNA requires BSE/TSE risk assessment per SCCS guidelines; fish- or plant-derived sources preferred for COSMOS/ECOCERT; purity and residual protein content should be specified in the PIF

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Concern Level: Low

Regulatory Flags

natural-origin

Frequently Asked Questions

Is DNA safe in cosmetics?

Source-origin documentation essential: bovine-derived DNA requires BSE/TSE risk assessment per SCCS guidelines; fish- or plant-derived sources preferred for COSMOS/ECOCERT; purity and residual protein content should be specified in the PIF The EU classifies DNA as "permitted". Safety rating: GOOD.

Is DNA allowed in the EU?

DNA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does DNA do in cosmetics?

DNA functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 9007-49-2.

What is the Margin of Safety for DNA?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for DNA in your formulation.