Elaidoyl Tripeptide-37

INCI: ELAIDOYL TRIPEPTIDE-37

CAS Number
Not publicly assigned (proprietary synthetic lipopeptide; trade name: Lipospondin)
Function
Skin conditioning — stimulates TGF-β, promotes collagen/elastin production, inhibits MMPs
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction; CIR reviewed peptide class (Tripeptide-1, Hexapeptide-12 and related lipopeptides) as safe in present practices of use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Elaidic acid moiety is a trans-fatty acid with topical use only; no concern at cosmetic concentrations. No specific genotoxicity or reproductive toxicity data for this exact INCI; relies on read-across from palmitoyl peptide analogs.

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Concern Level: Low

Frequently Asked Questions

Is Elaidoyl Tripeptide-37 safe in cosmetics?

Elaidic acid moiety is a trans-fatty acid with topical use only; no concern at cosmetic concentrations. No specific genotoxicity or reproductive toxicity data for this exact INCI; relies on read-across from palmitoyl peptide analogs. The EU classifies Elaidoyl Tripeptide-37 as "permitted". Safety rating: GOOD.

Is Elaidoyl Tripeptide-37 allowed in the EU?

Elaidoyl Tripeptide-37 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Elaidoyl Tripeptide-37 do in cosmetics?

Elaidoyl Tripeptide-37 functions as: Skin conditioning — stimulates TGF-β, promotes collagen/elastin production, inhibits MMPs. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (proprietary synthetic lipopeptide; trade name: Lipospondin).

What is the Margin of Safety for Elaidoyl Tripeptide-37?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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