Regulatory Status
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Safety Data
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Expert Verdict
Protein allergenicity cannot be fully excluded; ensure endotoxin-free production; stability and activity are highly pH and temperature-dependent; encapsulation integrity is critical for both efficacy and safety
Regulatory Flags
Frequently Asked Questions
Is Endonuclease V safe in cosmetics?
Protein allergenicity cannot be fully excluded; ensure endotoxin-free production; stability and activity are highly pH and temperature-dependent; encapsulation integrity is critical for both efficacy and safety The EU classifies Endonuclease V as "restricted". Safety rating: GOOD.
Is Endonuclease V allowed in the EU?
Endonuclease V EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Endonuclease V do in cosmetics?
Endonuclease V functions as: Skin protecting — DNA repair enzyme that cleaves abasic sites in UV-damaged DNA. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for cosmetic grade; enzyme EC 3.2.2.28.
What is the Margin of Safety for Endonuclease V?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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