Epidermis Lipids

INCI: EPIDERMIS LIPIDS

CAS Number
No single CAS — this is a complex mixture term. Composition varies by manufacturer (typically includes ceramides, cholesterol, free fatty acids, and/or phytosphingosine)
Function
Skin conditioning, skin-identical lipid replacement, barrier repair, emollient
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no FDA restriction; must comply with general cosmetic safety requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Origin verification is critical — can be synthetic, plant-derived, or animal-derived (bovine/porcine). Animal origin creates regulatory complexity (BSE/TSE compliance, Nagoya Protocol, religious/vegan labeling). Synthetic or plant-derived sources are strongly preferred for COSMOS/ECOCERT compliance. Supplier must provide full composition breakdown since Epidermis Lipids is a generic term covering variable mixtures.

⚠️
Concern Level: Low

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Epidermis Lipids safe in cosmetics?

Origin verification is critical — can be synthetic, plant-derived, or animal-derived (bovine/porcine). Animal origin creates regulatory complexity (BSE/TSE compliance, Nagoya Protocol, religious/vegan labeling). Synthetic or plant-derived sources are strongly preferred for COSMOS/ECOCERT compliance. Supplier must provide full composition breakdown since Epidermis Lipids is a generic term covering variable mixtures. The EU classifies Epidermis Lipids as "permitted". Safety rating: EXCELLENT.

Is Epidermis Lipids allowed in the EU?

Epidermis Lipids EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Epidermis Lipids do in cosmetics?

Epidermis Lipids functions as: Skin conditioning, skin-identical lipid replacement, barrier repair, emollient. It is classified as a cosmetic ingredient in our database. CAS number: No single CAS — this is a complex mixture term. Composition varies by manufacturer (typically includes ceramides, cholesterol, free fatty acids, and/or phytosphingosine).

What is the Margin of Safety for Epidermis Lipids?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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