Epigaea Repens Leaf Extract

INCI: EPIGAEA REPENS LEAF EXTRACT

CAS Number
Not widely assigned (botanical extract; no EINECS entry)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.02% (as hydroquinone impurity)
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific 21 CFR restriction; safe-use history as traditional botanical

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Arbutin content may release free hydroquinone upon degradation (hydroquinone is restricted under Annex III with max 0.02% as impurity in botanical extracts). Limited published toxicological data; full toxicological dossier required for CPSR.

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Epigaea Repens Leaf Extract safe in cosmetics?

Arbutin content may release free hydroquinone upon degradation (hydroquinone is restricted under Annex III with max 0.02% as impurity in botanical extracts). Limited published toxicological data; full toxicological dossier required for CPSR. The EU classifies Epigaea Repens Leaf Extract as "restricted". Safety rating: MODERATE.

Is Epigaea Repens Leaf Extract allowed in the EU?

Epigaea Repens Leaf Extract EU regulatory status: restricted. Maximum allowed concentration: 0.02% (as hydroquinone impurity). This is based on EU Regulation 1223/2009 and its amendments.

What does Epigaea Repens Leaf Extract do in cosmetics?

Epigaea Repens Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not widely assigned (botanical extract; no EINECS entry).

What is the Margin of Safety for Epigaea Repens Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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