Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media

INCI: EPIGALLOCATECHIN GALLATE/BIOTIN/COLLAGEN/MOUSE FIBROBLAST CONDITIONED MEDIA

CAS Number
No single CAS for this complex blend (EGCG alone: 989-51-5)
Function
Skin conditioning, anti-aging, anti-wrinkle
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - Not specifically prohibited. Biological ingredients from animal cell culture are permitted in cosmetics but must meet safety requirements.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mouse-derived biological material carries risks of allergenic proteins, pathogen transmission, and batch-to-batch variability. EGCG is a potent antioxidant but can be pro-oxidant at high concentrations. The conditioned media contains growth factors, whose long-term topical effects are still under investigation.. Combines EGCG's antioxidant and anti-melanogenic properties with biotin (vitamin B7), collagen for structural support, and fibroblast-conditioned media containing growth factors and e...

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media safe in cosmetics?

Mouse-derived biological material carries risks of allergenic proteins, pathogen transmission, and batch-to-batch variability. EGCG is a potent antioxidant but can be pro-oxidant at high concentrations. The conditioned media contains growth factors, whose long-term topical effects are still under investigation.. Combines EGCG's antioxidant and anti-melanogenic properties with biotin (vitamin B7), collagen for structural support, and fibroblast-conditioned media containing growth factors and e... The EU classifies Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media as "permitted". Safety rating: MODERATE.

Is Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media allowed in the EU?

Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media do in cosmetics?

Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media functions as: Skin conditioning, anti-aging, anti-wrinkle. It is classified as a cosmetic ingredient in our database. CAS number: No single CAS for this complex blend (EGCG alone: 989-51-5).

What is the Margin of Safety for Epigallocatechin Gallate/Biotin/Collagen/Mouse Fibroblast Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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