Is Equol safe in cosmetics?
Equol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Equol
INCI: EQUOL
Equol (CAS 94105-90-5 (racemic); 531-95-3 (S-equol) [^1_1][^1_2]) is a cosmetic cosmetic ingredient functioning as Skin conditioning — antioxidant, estrogen-receptor ligand (ERβ-selective. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
94105-90-5 (racemic); 531-95-3 (S-equol) [^1_1][^1_2]
View industrial chemical safety profile →
Function
Skin conditioning — antioxidant, estrogen-receptor ligand (ERβ-selective isoflavandiol metabolite of daidzein)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not listed in 21 CFR §700.11–.27 (prohibited/restricted). No CIR final report.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Equol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Equol.
Regulatory Flags
endocrine_disruptor
Frequently Asked Questions
Is Equol allowed in the EU?
Equol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Equol do in cosmetics?
Equol functions as: Skin conditioning — antioxidant, estrogen-receptor ligand (ERβ-selective isoflavandiol metabolite of daidzein). It is classified as a cosmetic ingredient in our database. CAS number: 94105-90-5 (racemic); 531-95-3 (S-equol) [^1_1][^1_2].
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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