Yerba Santa Leaf Extract

INCI: ERIODICTYON CALIFORNICUM LEAF EXTRACT

CAS Number
68990-14-7
Function
Skin conditioning, antioxidant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No FDA monograph or OTC classification; permitted under general FDCA provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Promising botanical with good anti-inflammatory and antioxidant evidence via eriodictyol (Nrf2/HO-1 pathway); non-cytotoxic up to 40 µM in fibroblasts; UV-protective in keratinocytes; no SCCS or CIR review but favorable in vitro profile.

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Concern Level: Low

Regulatory Flags

antioxidant anti-inflammatory soothing eriodictyol uv-protective no-sccs-opinion no-cir-review data-gaps botanical

Frequently Asked Questions

Is Yerba Santa Leaf Extract safe in cosmetics?

Promising botanical with good anti-inflammatory and antioxidant evidence via eriodictyol (Nrf2/HO-1 pathway); non-cytotoxic up to 40 µM in fibroblasts; UV-protective in keratinocytes; no SCCS or CIR review but favorable in vitro profile. The EU classifies Yerba Santa Leaf Extract as "permitted". Safety rating: GOOD.

Is Yerba Santa Leaf Extract allowed in the EU?

Yerba Santa Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Yerba Santa Leaf Extract do in cosmetics?

Yerba Santa Leaf Extract functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 68990-14-7.

What is the Margin of Safety for Yerba Santa Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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