Ethoxydiglycol Isostearate

INCI: ETHOXYDIGLYCOL ISOSTEARATE

CAS Number
Not uniquely assigned in public databases — verify via CosIng/supplier CoA
Function
Skin conditioning – emollient; co-solvent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted. CIR Expert Panel reviewed ethoxydiglycol esters in the context of the glycol ether group; ethoxydiglycol itself deemed safe at 0.0004–80%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential hydrolysis to ethoxydiglycol (EU-restricted). EU SCCS flagged DEGEE as a penetration enhancer that may co-transport harmful substances. Ethylene glycol impurity limits apply to DEGEE-derived ingredients.

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Concern Level: Moderate

Frequently Asked Questions

Is Ethoxydiglycol Isostearate safe in cosmetics?

Potential hydrolysis to ethoxydiglycol (EU-restricted). EU SCCS flagged DEGEE as a penetration enhancer that may co-transport harmful substances. Ethylene glycol impurity limits apply to DEGEE-derived ingredients. The EU classifies Ethoxydiglycol Isostearate as "restricted". Safety rating: MODERATE.

Is Ethoxydiglycol Isostearate allowed in the EU?

Ethoxydiglycol Isostearate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethoxydiglycol Isostearate do in cosmetics?

Ethoxydiglycol Isostearate functions as: Skin conditioning – emollient; co-solvent. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned in public databases — verify via CosIng/supplier CoA.

What is the Margin of Safety for Ethoxydiglycol Isostearate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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