Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate

INCI: ETHYL 2-METHYL-4-OXO-6-PENTYLCYCLOHEX-2-ENECARBOXYLATE

CAS Number
Verify via PubChem CID 100968 — multiple CAS entries exist for stereoisomers [^1_10]
Function
Fragrance / synthetic intermediate
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Uncertain — no specific CFR listing found

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

α,β-unsaturated carbonyl is a known skin sensitization structural alert. ECHA C&L notifications include H317 (may cause allergic skin reaction) for related structures. The pentyl chain and ketone functionality resemble cannabinoid precursors — confirm regulatory intent and end-use. Full LLNA/DPRA and repeat-dose data required.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate safe in cosmetics?

α,β-unsaturated carbonyl is a known skin sensitization structural alert. ECHA C&L notifications include H317 (may cause allergic skin reaction) for related structures. The pentyl chain and ketone functionality resemble cannabinoid precursors — confirm regulatory intent and end-use. Full LLNA/DPRA and repeat-dose data required. The EU classifies Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate as "permitted". Safety rating: POOR.

Is Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate allowed in the EU?

Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate do in cosmetics?

Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate functions as: Fragrance / synthetic intermediate. It is classified as a cosmetic ingredient in our database. CAS number: Verify via PubChem CID 100968 — multiple CAS entries exist for stereoisomers [^1_10].

What is the Margin of Safety for Ethyl 2-Methyl-4-oxo-6-pentylcyclohex-2-enecarboxylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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