Ethyl Caffeate

INCI: ETHYL CAFFEATE

CAS Number
102-37-4 [^1_14][^1_15]
Function
Antioxidant and anti-inflammatory active
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS hazards include H302 (harmful if swallowed), H315 (skin irritation), H319 (eye irritation), H332 (harmful if inhaled), and H335 (respiratory irritation). The catechol structure presents a sensitization alert. Primarily used in pharmaceutical research with limited cosmetic application. HRIPT or LLNA data required for CPSR support.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Ethyl Caffeate safe in cosmetics?

GHS hazards include H302 (harmful if swallowed), H315 (skin irritation), H319 (eye irritation), H332 (harmful if inhaled), and H335 (respiratory irritation). The catechol structure presents a sensitization alert. Primarily used in pharmaceutical research with limited cosmetic application. HRIPT or LLNA data required for CPSR support. The EU classifies Ethyl Caffeate as "permitted". Safety rating: MODERATE.

Is Ethyl Caffeate allowed in the EU?

Ethyl Caffeate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Caffeate do in cosmetics?

Ethyl Caffeate functions as: Antioxidant and anti-inflammatory active. It is classified as a cosmetic ingredient in our database. CAS number: 102-37-4 [^1_14][^1_15].

What is the Margin of Safety for Ethyl Caffeate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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