Ethyl Estradiolcarboxylate

INCI: ETHYL ESTRADIOLCARBOXYLATE

CAS Number
Not widely catalogued (estradiol derivative / hormonal ester)
Function
Estrogenic hormone derivative
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Effectively prohibited โ€” FDA considers hormones as drug ingredients; estrogen-containing topical products require NDA/OTC monograph compliance; not permitted in cosmetics.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL โ€” Endocrine disruptor; estrogenic activity at very low doses; associated with hormone-dependent cancers; illegal addition to cosmetics is subject to enforcement action in both EU and US; any detection results in product recall.

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Concern Level: High

Frequently Asked Questions

Is Ethyl Estradiolcarboxylate safe in cosmetics?

CRITICAL โ€” Endocrine disruptor; estrogenic activity at very low doses; associated with hormone-dependent cancers; illegal addition to cosmetics is subject to enforcement action in both EU and US; any detection results in product recall. The EU classifies Ethyl Estradiolcarboxylate as "prohibited". Safety rating: POOR.

Is Ethyl Estradiolcarboxylate allowed in the EU?

Ethyl Estradiolcarboxylate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Estradiolcarboxylate do in cosmetics?

Ethyl Estradiolcarboxylate functions as: Estrogenic hormone derivative. It is classified as a cosmetic ingredient in our database. CAS number: Not widely catalogued (estradiol derivative / hormonal ester).

What is the Margin of Safety for Ethyl Estradiolcarboxylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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