Ethyl Ferulate

Also known as: 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester, Ethyl 4'-hydroxy-3'-methoxycinnamate, EINECS 223-745-5

INCI: ETHYL FERULATE

Ethyl Ferulate (CAS 4046-02-0) is a cosmetic cosmetic ingredient functioning as Antioxidant, UV Absorber, Anti-inflammatory. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 4046-02-0 →

Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, UV Absorber, Anti-inflammatory
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C12H14O4
MW
222.24 g/mol
PubChem CID
736681
IUPAC Name
ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
InChIKey
ATJVZXXHKSYELS-FNORWQNLSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes No CIR safety assessment published; permitted as general cosmetic antioxidant; not approved as OTC sunscreen active

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Ferulate.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

1 property record from structured ingredient metadata.

anti_pollution
{"cas_number": "4046-02-0", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5/UV_A", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modu…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant Preservative

Expert Verdict

Expert safety assessment and concern-level summary for Ethyl Ferulate.

Regulatory Flags

no-annex-vi-listing cannot-claim-uv-filter-eu no-sccs-opinion no-cir-report cosmos-approved lipophilic-oil-phase

Known Synonyms

2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester Ethyl 4'-hydroxy-3'-methoxycinnamate EINECS 223-745-5

Chemical Function

Antioxidant Preservative

Regulatory Lists

Canada; pharmaceutical Canada; pharmaceutical

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
ETHYL FERULATE
ChEMBL ID
CHEMBL286796
View full pharmaceutical profile →

Frequently Asked Questions

Is Ethyl Ferulate safe in cosmetics?

Ethyl Ferulate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Ethyl Ferulate allowed in the EU?

Ethyl Ferulate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Ferulate do in cosmetics?

Ethyl Ferulate functions as: Antioxidant, UV Absorber, Anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: 4046-02-0.

Is Ethyl Ferulate used outside cosmetics?

Ethyl Ferulate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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Perfuming
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Solvent

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