Ethylbisiminomethylguaiacol Manganese Chloride

INCI: ETHYLBISIMINOMETHYLGUAIACOL MANGANESE CHLORIDE

CAS Number
81065-76-1
Function
Antioxidant superoxide dismutase (SOD) and catalase mimetic
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted, not specifically restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Australian AICIS restricts to โ‰ค0.002% in dermal cosmetics and prohibits use in eye-area products; manganese ion release poses concerns at higher concentrations; supplier-reported use levels of 0.01โ€“0.05% in powder formulations exceed the AICIS-assessed limit and require reconciliation.

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Concern Level: Moderate

Frequently Asked Questions

Is Ethylbisiminomethylguaiacol Manganese Chloride safe in cosmetics?

Australian AICIS restricts to โ‰ค0.002% in dermal cosmetics and prohibits use in eye-area products; manganese ion release poses concerns at higher concentrations; supplier-reported use levels of 0.01โ€“0.05% in powder formulations exceed the AICIS-assessed limit and require reconciliation. The EU classifies Ethylbisiminomethylguaiacol Manganese Chloride as "restricted". Safety rating: MODERATE.

Is Ethylbisiminomethylguaiacol Manganese Chloride allowed in the EU?

Ethylbisiminomethylguaiacol Manganese Chloride EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylbisiminomethylguaiacol Manganese Chloride do in cosmetics?

Ethylbisiminomethylguaiacol Manganese Chloride functions as: Antioxidant superoxide dismutase (SOD) and catalase mimetic. It is classified as a cosmetic ingredient in our database. CAS number: 81065-76-1.

What is the Margin of Safety for Ethylbisiminomethylguaiacol Manganese Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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