Ethylhexyl Benzyldioxopiperazyl Acetate

INCI: ETHYLHEXYL BENZYLDIOXOPIPERAZYL ACETATE

CAS Number
Not widely published (GSRS identifier: MF41BFB17F; trade name: NOMCORT)
Function
Emollient, skin conditioning agent, solvent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR prohibition; limited CIR-specific review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gap alert. Very limited publicly available toxicological data. No CIR review identified. No SCCS opinion located. CPSR assessor must request full supplier-provided safety dossier including acute toxicity, irritation, sensitization, genotoxicity, and repeat-dose data. Diketopiperazine scaffold requires structure-activity evaluation.

โš ๏ธ
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Ethylhexyl Benzyldioxopiperazyl Acetate safe in cosmetics?

Data gap alert. Very limited publicly available toxicological data. No CIR review identified. No SCCS opinion located. CPSR assessor must request full supplier-provided safety dossier including acute toxicity, irritation, sensitization, genotoxicity, and repeat-dose data. Diketopiperazine scaffold requires structure-activity evaluation. The EU classifies Ethylhexyl Benzyldioxopiperazyl Acetate as "permitted". Safety rating: MODERATE.

Is Ethylhexyl Benzyldioxopiperazyl Acetate allowed in the EU?

Ethylhexyl Benzyldioxopiperazyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylhexyl Benzyldioxopiperazyl Acetate do in cosmetics?

Ethylhexyl Benzyldioxopiperazyl Acetate functions as: Emollient, skin conditioning agent, solvent. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (GSRS identifier: MF41BFB17F; trade name: NOMCORT).

What is the Margin of Safety for Ethylhexyl Benzyldioxopiperazyl Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Ethylhexyl Benzyldioxopiperazyl Acetate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ethylhexyl Benzyldioxopiperazyl Acetate in your formulation.