Is Stevia Leaf Extract safe in cosmetics?
Stevia Leaf Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Stevia Leaf Extract
INCI: EUPATORIUM REBAUDIANUM LEAF EXTRACT
Stevia Leaf Extract (CAS 92332-31-5) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Antioxidant, Anti-inflammatory. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 92332-31-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Antioxidant, Anti-inflammatory
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
InChIKey
HELXLJCILKEWJH-NCGAPWICSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated by FDA for cosmetic use; purified steviol glycosides hold food GRAS status but crude leaf extracts do not
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Stevia Leaf Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
REBAUDIOSIDE A | 2023 | 0–4 mg/kg bw | Considered for specification only. | TRS 1050-JECFA 96/37 | FAS 73 JECFA 82/181
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Expert Verdict
Expert safety assessment and concern-level summary for Stevia Leaf Extract.
Regulatory Flags
plant-extract
stevia-synonym
no-sccs-opinion
no-cir-report
dermal-absorption-data-gap
sensitization-data-gap
cosmos-eligible
Frequently Asked Questions
Is Stevia Leaf Extract allowed in the EU?
Stevia Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Stevia Leaf Extract do in cosmetics?
Stevia Leaf Extract functions as: Skin Conditioning, Antioxidant, Anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: 92332-31-5.
Is Stevia Leaf Extract used outside cosmetics?
Stevia Leaf Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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