Eurycoma Longifolia Root Extract

INCI: EURYCOMA LONGIFOLIA ROOT EXTRACT

CAS Number
Not specifically assigned for extract; eurycomanone CAS 84633-29-4
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not in 21 CFR as prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: EFSA NDA Panel concluded the ingredient has the potential to induce DNA damage, which is of concern, particularly locally for tissues that represent first sites of contact. Positive in vitro chromosomal aberration test and in vivo comet assay support genotoxic potential. A CPSR assessor would likely reject this ingredient without robust negative Ames/micronucleus data specific to cosmetic-grade material.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Eurycoma Longifolia Root Extract safe in cosmetics?

CRITICAL: EFSA NDA Panel concluded the ingredient has the potential to induce DNA damage, which is of concern, particularly locally for tissues that represent first sites of contact. Positive in vitro chromosomal aberration test and in vivo comet assay support genotoxic potential. A CPSR assessor would likely reject this ingredient without robust negative Ames/micronucleus data specific to cosmetic-grade material. The EU classifies Eurycoma Longifolia Root Extract as "permitted". Safety rating: POOR.

Is Eurycoma Longifolia Root Extract allowed in the EU?

Eurycoma Longifolia Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Eurycoma Longifolia Root Extract do in cosmetics?

Eurycoma Longifolia Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for extract; eurycomanone CAS 84633-29-4.

What is the Margin of Safety for Eurycoma Longifolia Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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