Fallopia Japonica Root Extract

INCI: FALLOPIA JAPONICA ROOT EXTRACT

CAS Number
91770-89-3 (also listed under Polygonum cuspidatum)
Function
Skin Conditioning, Antioxidant, Anti-inflammatory
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific FDA restrictions; widely used as resveratrol source in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Emodin content: Anthraquinone derivative with genotoxicity signals (Ames-positive in some studies); phototoxicity potential; extract standardization is critical as crude extracts may contain problematic anthraquinone levels. Japanese knotweed is also an invasive species, which may affect supply chain sustainability documentation.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Fallopia Japonica Root Extract safe in cosmetics?

Emodin content: Anthraquinone derivative with genotoxicity signals (Ames-positive in some studies); phototoxicity potential; extract standardization is critical as crude extracts may contain problematic anthraquinone levels. Japanese knotweed is also an invasive species, which may affect supply chain sustainability documentation. The EU classifies Fallopia Japonica Root Extract as "prohibited". Safety rating: GOOD.

Is Fallopia Japonica Root Extract allowed in the EU?

Fallopia Japonica Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Fallopia Japonica Root Extract do in cosmetics?

Fallopia Japonica Root Extract functions as: Skin Conditioning, Antioxidant, Anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: 91770-89-3 (also listed under Polygonum cuspidatum).

What is the Margin of Safety for Fallopia Japonica Root Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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