Feruloyl Oligopeptide-33

INCI: FERULOYL OLIGOPEPTIDE-33

CAS Number
Not assigned / not publicly listed
Function
Skin conditioning (peptide conjugated with ferulic acid moiety — anticipated antioxidant and signaling peptide activity)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no FDA prohibition; no specific CFR listing; manufacturer bears safety substantiation obligation under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CIR review or SCCS opinion available; no published acute, repeat-dose, genotoxicity, or reproductive data; CPSR assessor would require manufacturer-supplied in-vitro safety dossier (e.g., h-CLAT, KeratinoSens, Ames test)

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Feruloyl Oligopeptide-33 safe in cosmetics?

No CIR review or SCCS opinion available; no published acute, repeat-dose, genotoxicity, or reproductive data; CPSR assessor would require manufacturer-supplied in-vitro safety dossier (e.g., h-CLAT, KeratinoSens, Ames test) The EU classifies Feruloyl Oligopeptide-33 as "permitted". Safety rating: MODERATE.

Is Feruloyl Oligopeptide-33 allowed in the EU?

Feruloyl Oligopeptide-33 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Feruloyl Oligopeptide-33 do in cosmetics?

Feruloyl Oligopeptide-33 functions as: Skin conditioning (peptide conjugated with ferulic acid moiety — anticipated antioxidant and signaling peptide activity). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly listed.

What is the Margin of Safety for Feruloyl Oligopeptide-33?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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