Is Fluridil safe in cosmetics?
Fluridil has a safety rating of "GOOD" in our database. EU status: prohibited. US status: prohibited.
Good
Cosmetic Ingredient
Fluridil
Also known as: 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(2,2,2-trifluoroacetamido)propanamide, Propanamide, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)amino]-, BP 766
INCI: FLURIDIL
Fluridil (CAS 260980-89-0) is a cosmetic cosmetic ingredient functioning as Hair conditioning (topical anti-androgen receptor suppressor for androgenetic. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 260980-89-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Fluridil is prohibited in EU cosmetics but has active industrial GHS classifications (H319, H411).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair conditioning (topical anti-androgen receptor suppressor for androgenetic alopecia)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)amino]propanamide
InChIKey
YCNCRLKXSLARFT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not FDA-approved as drug or OTC ingredient; not explicitly prohibited in cosmetics but anti-androgenic claims would trigger drug classification
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Fluridil.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Fluridil.
Known Synonyms
2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(2,2,2-trifluoroacetamido)propanamide
Propanamide, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)amino]-
BP 766
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TOPILUTAMIDE
ChEMBL ID
CHEMBL2107790
Max Phase
2
Frequently Asked Questions
Is Fluridil allowed in the EU?
Fluridil EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Fluridil do in cosmetics?
Fluridil functions as: Hair conditioning (topical anti-androgen receptor suppressor for androgenetic alopecia). It is classified as a cosmetic ingredient in our database. CAS number: 260980-89-0.
Is Fluridil used outside cosmetics?
Fluridil also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Fluridil have different safety status in cosmetics vs industrial chemicals?
Fluridil is prohibited in EU cosmetics but has active industrial GHS classifications (H319, H411).
Compliance Tools
Check Fluridil compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2-Hydroxypropylcarbamato Amodimethicone
Excellent
Same category
Hair conditioning; modified aminosili...
Acetamidoamodimethicone
Excellent
Same category
Hair conditioning agent (film-forming...
Glyceryl Dioleate/Linoleate/Linolenate
Excellent
Same category
Hair conditioning agent
Gondoic Acid
Excellent
Same category
Hair conditioning
Hydroxypropyldimethicone
Excellent
Same category
Skin/hair conditioning (silicone poly...
Hydroxypropyltrimonium Inulin
Excellent
Same category
Antistatic, hair conditioning
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
FORSYTHIA VIRIDISSIMA FRUIT EXTRACT
Good
Browse nearby
Skin Conditioning
FORSYTHIA VIRIDISSIMA FRUIT/(ACTAEA DAHURICA/GLYCYRRHIZA GLABRA/PAEONIA LACTIFLORA/PLATYCODON GRANDIFLORUS/PUERARIA MONTANA) ROOT EXTRACT
Good
Browse nearby
Skin Conditioning
FORSYTHIA VIRIDISSIMA FRUIT/(ANGELICA ACUTILOBA/ACTAEA DAHURICA/GLYCYRRHIZA GLABRA/PAEONIA LACTIFLORA/PLATYCODON GRANDIFLORUS/PUERARIA MONTANA) ROOT EXTRACT
Good
Browse nearby
Skin Conditioning, Skin Conditioning ...
Is Fluridil in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Fluridil in your formulation.