Formamidopropyl Betaine

INCI: FORMAMIDOPROPYL BETAINE

CAS Number
Not widely published — verify via CosIng/PCPC dictionary
Function
Amphoteric surfactant / cleansing agent (betaine class)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Betaine surfactants are generally well-tolerated; CAPB analogues show adequate margin of safety at ≤6% in leave-on and ≤30% in rinse-off products. The formamido- prefix indicates formamide-derived chain head with potential for DMAPA-type impurities that must be controlled. Supplier CoA required to confirm impurity profile and CPSR must rely on read-across from CAPB/betaine class data.

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Concern Level: Moderate

Frequently Asked Questions

Is Formamidopropyl Betaine safe in cosmetics?

Betaine surfactants are generally well-tolerated; CAPB analogues show adequate margin of safety at ≤6% in leave-on and ≤30% in rinse-off products. The formamido- prefix indicates formamide-derived chain head with potential for DMAPA-type impurities that must be controlled. Supplier CoA required to confirm impurity profile and CPSR must rely on read-across from CAPB/betaine class data. The EU classifies Formamidopropyl Betaine as "permitted". Safety rating: MODERATE.

Is Formamidopropyl Betaine allowed in the EU?

Formamidopropyl Betaine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Formamidopropyl Betaine do in cosmetics?

Formamidopropyl Betaine functions as: Amphoteric surfactant / cleansing agent (betaine class). It is classified as a cosmetic ingredient in our database. CAS number: Not widely published — verify via CosIng/PCPC dictionary.

What is the Margin of Safety for Formamidopropyl Betaine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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