Ganoderma Lucidum Extract

INCI: GANODERMA LUCIDUM EXTRACT

CAS Number
223751-82-4
Function
Skin conditioning agent, emulsion stabilising agent, viscosity controlling agent, antioxidant, anti-aging
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR 2023 Final Report reference exists for mushroom extract variant; no specific FDA restrictions; treated as cosmetic ingredient under FD&C Act

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted with no restrictions. Oral safety well-characterized with NOAEL 2,000 mg/kg/day and negative genotoxicity studies; in vitro evidence supports MMP-1 inhibition and antioxidant activity. Dermal route remains under-characterized with limited published absorption and sensitization data for cosmetic-grade extracts.

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Concern Level: Low

Regulatory Flags

mushroom-extract reishi polysaccharides triterpenoids antioxidant anti-aging data-gaps extract-variability eu_children_restricted

Frequently Asked Questions

Is Ganoderma Lucidum Extract safe in cosmetics?

Permitted with no restrictions. Oral safety well-characterized with NOAEL 2,000 mg/kg/day and negative genotoxicity studies; in vitro evidence supports MMP-1 inhibition and antioxidant activity. Dermal route remains under-characterized with limited published absorption and sensitization data for cosmetic-grade extracts. The EU classifies Ganoderma Lucidum Extract as "permitted". Safety rating: GOOD.

Is Ganoderma Lucidum Extract allowed in the EU?

Ganoderma Lucidum Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ganoderma Lucidum Extract do in cosmetics?

Ganoderma Lucidum Extract functions as: Skin conditioning agent, emulsion stabilising agent, viscosity controlling agent, antioxidant, anti-aging. It is classified as a cosmetic ingredient in our database. CAS number: 223751-82-4.

What is the Margin of Safety for Ganoderma Lucidum Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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