Ginkgo Biloba Nut Extract

INCI: GINKGO BILOBA NUT EXTRACT

CAS Number
90045-36-6 (general *Ginkgo biloba* CAS)
Function
Skin Conditioning, Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: INSUFFICIENT DATA to determine safety (2018 final report, reaffirmed 2024). Only 5 leaf-derived ingredients cleared; nut extract specifically flagged as data-insufficient.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR Expert Panel ruled data insufficient for this ingredient. Ginkgolic acid (alkylphenol/urushiol analog) at >5 ppm causes contact dermatitis; crude extracts can contain up to 30 ppm urushiol. Documented drug interactions with anticoagulants, NSAIDs, and SSRIs. Formulation must control ginkgolic acid levels rigorously to minimize sensitization risk.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Ginkgo Biloba Nut Extract safe in cosmetics?

CIR Expert Panel ruled data insufficient for this ingredient. Ginkgolic acid (alkylphenol/urushiol analog) at >5 ppm causes contact dermatitis; crude extracts can contain up to 30 ppm urushiol. Documented drug interactions with anticoagulants, NSAIDs, and SSRIs. Formulation must control ginkgolic acid levels rigorously to minimize sensitization risk. The EU classifies Ginkgo Biloba Nut Extract as "permitted". Safety rating: MODERATE.

Is Ginkgo Biloba Nut Extract allowed in the EU?

Ginkgo Biloba Nut Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginkgo Biloba Nut Extract do in cosmetics?

Ginkgo Biloba Nut Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 90045-36-6 (general *Ginkgo biloba* CAS).

What is the Margin of Safety for Ginkgo Biloba Nut Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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